Preheat your oven to 375°F (190°C) and grease a loaf pan or 9x13-inch baking dish.

In a large bowl, combine ground beef, salsa, cheddar cheese, diced green chiles, taco seasoning, crushed tortilla chips, eggs, onion, garlic, salt, and pepper. Mix thoroughly without overmixing.

Transfer the mixture into the loaf pan, shaping it into a neat loaf.

Bake uncovered for 45 to 55 minutes until the internal temperature reaches 160°F (71°C).

In the last 5 minutes, top with extra salsa or shredded cheese.

Let the meatloaf rest for about 10 minutes before slicing.

Slice and serve warm with desired toppings.