Preheat your oven to 350°F (175°C). Grease a 9x5-inch loaf pan with cooking spray or butter.

In a medium bowl, whisk together the flour, baking powder, baking soda, and salt.

In a large mixing bowl, combine granulated sugar with lemon zest. Rub the zest into the sugar until fragrant. Whisk in Greek yogurt, vegetable oil, eggs, lemon juice, and vanilla extract until smooth.

Gradually add the dry mixture into the wet mixture, folding gently to combine without overmixing.

Pour the batter into the prepared loaf pan and bake for 50 to 55 minutes, or until a toothpick comes out clean.

Let the loaf cool in the pan for about 10 minutes on a wire rack.

Prepare the glaze by whisking together powdered sugar and lemon juice. Adjust juice for desired consistency, and drizzle over the cooled loaf.